Substrate: Histone H2AFX (Histone H2A)
Seq-ID: P16104 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-56621   WRN_HUMAN
MINT-2843419   ATM_HUMAN
MINT-3378379   TP53B_HUMAN
MINT-7543857   XRCC1_HUMAN
MINT-7543888   TYDP1_HUMAN
MINT-7906555   FACD2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
histone binding,
enzyme binding		 nucleoplasm,
nucleosome		 nucleosome assembly,
cell aging,
DNA damage checkpoint,
positive regulation of DNA repair,
meiosis,
response to ionizing radiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 121 NIQAVLLPKKTSATVGPKAPS - 16083285
HTP
0.50
 - H2A
0.47
 - medium
T 124 AVLLPKKTSATVGPKAPSGGK - 16083285
HTP
0.03
 - -
0.56
 - medium
S 140 PSGGKKATQASQEY        ATM 11571274
LTP
0.57
 MOD_PIKK_1
 - -
0.66
 - medium
S 140 PSGGKKATQASQEY        - 17525332
HTP
0.57
 MOD_PIKK_1
 - -
0.66
 - medium

Substrate: Histone H2AFX (Histone H2A)
Seq-ID: P27661 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
damaged DNA binding XY body,
replication fork,
male germ cell nucleus,
nucleosome		 nucleosome assembly,
spermatogenesis,
meiosis,
double-strand break repair via homologous recombination
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 137 PKAPAVGKKASQASQEY     - 12792649
LTP
0.36
 - -
0.52
 - medium
S 140 PAVGKKASQASQEY        ATM 11571274
LTP
0.30
 MOD_PIKK_1
 - -
0.50
 - medium

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